A lorry has collided with a car, before hitting a house, on the A556 in Cheshire.
The driver of the Audi has sustained serious injuries following the incident on the A556 Chester Road at Tabley at around 9.30am this morning (6 January).
The driver of the HGV is believed to have sustained minor injuries.
A full closure is currently in place from the A5033 Northwich Road, to Lostock roundabout, and the road is expected to remain closed for several hours.
Motorist are advised to avoid the area.
Anyone who witnessed the collision, or anyone with any information that may assist the investigation, is asked to contact Cheshire Police on 101, quoting IML 605662 or visit https://www.cheshire.police.uk/tua/tell-us-about/