Jobs at Fujitsu's site in Crewe are at risk as the company announces plans to axe 1,800 UK posts.
The move by the IT giant has been criticised by the Unite union.
National officer for IT Ian Tonks said: “This is a hammer blow for these hardworking employees who have given their all to make the UK subsidiary highly profitable.
“It is not good news for the UK economy as the company says that it intends to offshore many of these jobs, with increased automation also responsible for job losses.
“Fujtsu’s main UK subsidiary made £85.6m profit last year and we see no reason for these job losses. Unite will be doing its utmost to fight for these jobs, as well as giving our members maximum support at this very worrying time.
“Fujitsu claims to be a responsible business - it needs to start acting like one. Its UK staff make the company excellent profits.
“They deserve to be treated better than ‘unit costs’ that need to be minimised. Fujitsu staff are saying they have had enough of job and income insecurity and of being denied a real voice in their working lives.
“They can rely on the backing of Unite in challenging Fujitsu’s actions.”